Bone lead as a biological marker in epidemiologic studies of chronic toxicity: conceptual paradigms.

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Bone lead as a biological marker in epidemiologic studies of chronic toxicity: conceptual paradigms.

The skeleton contains the majority of the body's lead burden in both children and adults. The half-life of lead in bone is in the range of years to decades, depending on bone type, metabolic state, and subject age, among other things. Measurement of skeletal lead has benefited greatly from the recent development of X-ray fluorescence (XRF) instruments that can make rapid, safe, accurate, and re...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1998

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.981061